Addison's disease is treated with what type of medication?

• A. Antibiotics
• B. Steroids (ends in 'one')
• C. Antidepressants
• D. Diuretics

Answer: (B)

Addison's disease is an adrenal insufficiency, so the treatment focuses on replacing the missing hormones the adrenal glands should produce. The main therapy is glucocorticoid replacement to restore cortisol activity—commonly hydrocortisone, with prednisone used in some cases. Because primary adrenal insufficiency often also means low aldosterone, a mineralocorticoid such as fludrocortisone is added to help maintain electrolytes and blood pressure. The other options don’t address the underlying hormone deficiency: antibiotics target infections, antidepressants treat mood disorders, and diuretics don’t correct the hormone shortfall and can worsen electrolyte imbalances. In times of illness or stress, steroid doses may need to be increased to prevent an adrenal crisis.