In diabetic ketoacidosis, the metabolic pattern typically includes:

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Multiple Choice

In diabetic ketoacidosis, the metabolic pattern typically includes:

Explanation:
In diabetic ketoacidosis, you see an anion gap metabolic acidosis driven by accumulation of ketoacids (beta-hydroxybutyrate and acetoacetate). These ketone bodies are organic acids that increase the unmeasured anions in the blood, deplete bicarbonate, and widen the anion gap. Ketosis is positive in this condition, reflecting ongoing ketone production from unleashed lipolysis. Clinically, this pattern accompanies hyperglycemia and dehydration, and while potassium may be high initially, total body potassium is actually depleted due to osmotic diuresis and shifts. If the profile showed a non-anion gap acidosis or lacked ketosis, it wouldn’t fit DKA.

In diabetic ketoacidosis, you see an anion gap metabolic acidosis driven by accumulation of ketoacids (beta-hydroxybutyrate and acetoacetate). These ketone bodies are organic acids that increase the unmeasured anions in the blood, deplete bicarbonate, and widen the anion gap. Ketosis is positive in this condition, reflecting ongoing ketone production from unleashed lipolysis. Clinically, this pattern accompanies hyperglycemia and dehydration, and while potassium may be high initially, total body potassium is actually depleted due to osmotic diuresis and shifts. If the profile showed a non-anion gap acidosis or lacked ketosis, it wouldn’t fit DKA.

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