In SIADH, what is the expected urine osmolality?

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Prepare for the Mark Klimek Electrolytes and Endocrine Test. Utilize flashcards, multiple choice questions, and detailed explanations for each query to enhance your understanding. Ace your exam!

Multiple Choice

In SIADH, what is the expected urine osmolality?

Explanation:
In SIADH, there is inappropriately high ADH, so the kidneys keep reabsorbing water even when serum osmolality is low. That water reabsorption concentrates the urine, so urine osmolality is increased. The urine becomes more concentrated than plasma because ADH promotes water reabsorption in the collecting ducts, leading to high urine osmolality (often well above 100 mOsm/kg, commonly >300 mOsm/kg). This contrasts with situations where ADH is suppressed and urine is dilute.

In SIADH, there is inappropriately high ADH, so the kidneys keep reabsorbing water even when serum osmolality is low. That water reabsorption concentrates the urine, so urine osmolality is increased. The urine becomes more concentrated than plasma because ADH promotes water reabsorption in the collecting ducts, leading to high urine osmolality (often well above 100 mOsm/kg, commonly >300 mOsm/kg). This contrasts with situations where ADH is suppressed and urine is dilute.

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